Scientists at the Raman Research Institute (RRI), Bengaluru, have developed a breakthrough technique to detect toxic molecules like Rhodamine B at extremely low concentrations using the "coffee-stain effect."
The RRI technique uses Surface-Enhanced Raman Spectroscopy (SERS) amplified by the natural coffee-stain pattern of dried droplets containing gold nanorods.
About the RRI Rhodamine-B Detection Research
Rhodamine B is a banned synthetic dye in food due to its toxic effects on skin, eyes, respiratory system, and its environmental persistence.
Monitoring illegal use of Rhodamine B is difficult as it often occurs in very low concentrations undetectable by standard techniques.
The RRI technique uses Surface-Enhanced Raman Spectroscopy (SERS) amplified by the natural coffee-stain pattern of dried droplets containing gold nanorods.
Gold nanorods aggregate in a ring pattern during evaporation, creating hotspots that amplify the Raman signal, enabling detection of extremely low dye levels (down to 1 part per trillion).
The technique is simple, cost-effective, and potentially applicable with portable devices for field testing.
Beyond Rhodamine B, this approach could detect other contaminants in food, water, and the environment, aiding regulatory and public health efforts.
Health and Environmental Relevance of Rhodamine B
Causes DNA damage and mutations, linked to cancerous growths in animal studies.
Can provoke allergic reactions and skin pigmentation changes on prolonged exposure.
Persistent environmental pollutant, challenging to detect in natural water bodies.