Mammogram
 
Why in News?
The American College of Physicians (ACP) updated its guidance, recommending biennial (every two years) mammograms for average-risk women aged 50 to 74. This has sparked debate, as other major groups still recommend starting at age 40.
 

Core Function
  • Screening Tool: Used for patients with no symptoms to catch cancer up to three years before a lump can be felt.
  • Diagnostic Tool: Used to investigate specific symptoms like a lump, pain, nipple discharge, or skin changes.
  • Detection: It is the only tool that can reliably detect calcifications, which are often the earliest signs of cancer. 
Recent Screening Recommendations (2026)
Organisation  Recommended Starting Age Frequency
ACP (2026) 50 (40–49 is individual choice) Every 2 years
USPSTF (2024) 40 Every 2 years
ACR & NCCN 40 Every year
ACS 45 (Option to start at 40) Annual; Biennial after 55
 
Advanced Technologies
  • 3D Mammography (Tomosynthesis): Takes multiple X-rays from different angles to create a "sliced" 3D view. It is more accurate for dense breast tissue.
  • AI Integration: AI software now assists radiologists by flagging suspicious areas and predicting a woman’s 5-year cancer risk from a single scan.
  • Contrast-Enhanced Mammography (CEM): Uses an iodine-based dye to highlight abnormal blood flow around tumours, similar to an MRI but at a lower cost. 
Risks and Limitations
  • False Positives: A mammogram may look abnormal when no cancer is present, leading to "call-backs" and unnecessary biopsies.
  • False Negatives: Mammograms miss roughly 15%–20% of breast cancers, particularly in very dense breasts.
  • Radiation: While it uses radiation, the dose is extremely low and considered safe for regular annual or biennial use. 

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