Definition: COPD is a group of lung diseases that cause airflow blockage and breathing-related problems. The two main types are chronic bronchitis (inflammation of airways) and emphysema (damage to air sacs in the lungs).
Global impact: It is the fourth leading cause of death worldwide, responsible for 3.5 million deaths in 2021.
Progression: COPD worsens over time, but early diagnosis and treatment can slow progression.
Causes and Risk Factors
Smoking: The leading cause, accounting for over 70% of cases in high-income countries.
Air pollution: Household air pollution (from biomass fuels) is a major risk factor in low- and middle-income countries.
Occupational exposure: Long-term exposure to dust, fumes, or chemicals.
Genetics: Rarely, conditions like alpha-1 antitrypsin deficiency can predispose individuals to COPD.
Symptoms
Persistent cough with mucus
Shortness of breath, especially during physical activity
Wheezing (whistling sound while breathing)
Chest tightness
Frequent respiratory infections
Diagnosis
Spirometry test: Measures airflow and lung function.
Chest X-ray or CT scan: Helps detect emphysema and rule out other conditions.
Blood tests: May check oxygen levels or genetic risk factors.
Treatment and Management
Lifestyle changes: Quitting smoking is the most important step.
Medications: Bronchodilators, inhaled steroids, and combination inhalers.
Pulmonary rehabilitation: Exercise, nutrition, and breathing techniques.
Oxygen therapy: For advanced cases with low oxygen levels.
Surgery: In severe cases, lung volume reduction or transplant.