
| Feature | Archaea | Bacteria | Eukarya |
|---|---|---|---|
| Cell type | Prokaryotic | Prokaryotic | Eukaryotic |
| Nucleus | Absent | Absent | Present |
| Membrane lipids | Ether-linked | Ester-linked | Ester-linked |
| Cell wall | No peptidoglycan (varies) | Peptidoglycan | Cellulose (plants) or none |
| Extremophiles | Common | Rare | Rare |
| Pathogenic species | None known | Many | Some (fungi, protozoa) |
| Genetic similarity | Closer to eukaryotes | Distinct | Self |